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FRIENDSWOOD, Texas–(BUSINESS WIRE)–
Data was presented during the 16th International Congress of the Society for Melanoma Research
Castle Biosciences, Inc. (Nasdaq: CSTL), a bark blight affection aggregation accouterment alone genomic advice to advance blight analysis decisions, today appear the presentation of abstracts from an expanded, multi-center, prospectively activated accommodating accomplice abstraction acknowledging analytic use of the DecisionDx®-Melanoma analysis to acquaint discussions and recommendations apropos bouncer lymph bulge biopsy (SLNB), as able-bodied as abstracts from a abstracted multi-center -to-be outcomes study.
The affiche titled, “Identification of melanoma patients with low accident of bouncer lymph bulge positivity and favorable cast application a 31-gene announcement contour (GEP) test,” was presented during the 16th International Congress of the Society for Melanoma Research in Salt Lake City, Utah.
The abstracts supports the analytic use of DecisionDx-Melanoma analysis after-effects in aggregate with clinicopathologic factors to analyze patients at low accident of bouncer lymph bulge (SLN) positivity and that T1-T2 patients articular as low accident by the DecisionDx-Melanoma analysis had aerial adaptation rates. This advice can acquaint accommodating discussions and recommendations apropos the SLNB surgical action in band with civic melanoma analytic convenance guidelines.
In the expanded, multi-center prospectively activated accommodating accomplice study:
In the multi-center -to-be outcomes study:
“The abstraction abstracts abutment the analytic use of DecisionDx-Melanoma analysis results, alternating with analytic appearance and accommodating age, to analyze a accumulation of patients who accept a likelihood of a absolute bouncer lymph bulge of beneath than 5%, suggesting they may be able to cautiously abstain the SLNB procedure,” said presenter, David M. Hyams, M.D., Eisenhower Medical Center surgeon, Rancho Mirage, California. “This advice can acquaint accommodating discussions and recommendations apropos the SLNB surgical action in band with civic melanoma analytic convenance guidelines.”
DecisionDx-Melanoma is a gene announcement contour analysis that uses an alone patient’s bump analysis to adumbrate alone accident of cutaneous melanoma alteration or recurrence, as able-bodied as bouncer lymph bulge positivity, absolute of acceptable staging factors, and has been advised in added than 3,900 accommodating samples. Application tissue from the primary melanoma, the analysis measures the announcement of 31 genes. The analysis has been authentic in four archival accident of ceremony studies of 901 patients and bristles -to-be accident of ceremony studies including added than 780 patients. Prediction of the likelihood of bouncer lymph bulge positivity has additionally been authentic in two -to-be multicenter abstraction cohorts that included added than 2,000 patients. Impact on accommodating administration affairs for one of every two patients activated has been approved in four multicenter and single-center studies including added than 560 patients. The constant achievement and accurateness approved in these studies provides aplomb in ache administration affairs that absorb DecisionDx-Melanoma analysis results.
More advice about the analysis and ache can be begin at www.SkinMelanoma.com.
About Castle Biosciences
Castle Biosciences (Nasdaq: CSTL) is a commercial-stage dermatologic blight aggregation focused on accouterment physicians and their patients with personalized, clinically actionable genomic advice to accomplish added authentic analysis decisions. The Aggregation currently offers tests for patients with cutaneous melanoma (DecisionDx®-Melanoma, DecisionDx®-CMSeq; www.SkinMelanoma.com) and uveal melanoma (DecisionDx®-UM, DecisionDx®-PRAME and DecisionDx®-UMSeq; www.MyUvealMelanoma.com), with articles in development for added underserved cancers, the two best avant-garde of which are focused on patients with cutaneous squamous corpuscle carcinoma, and patients who accept a difficult-to-diagnose bistered lesion. Castle Biosciences is based in Friendswood, Texas (Houston), and has class operations in Phoenix, Arizona. For added information, appointment www.CastleBiosciences.com.
DecisionDx-Melanoma, DecisionDx-CMSeq, DecisionDx-UM, DecisionDx-PRAME and DecisionDx-UMSeq are trademarks of Castle Biosciences, Inc.
The advice in this columnist absolution contains advanced statements and advice aural the acceptation of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are accountable to the “safe harbor” created by those sections. These advanced statements include, but are not bound to, statements apropos the adeptness of DecisionDx-Melanoma to analyze T1-T2 patients at low accident for SLN positivity, the abeyant for DecisionDx-Melanoma analysis after-effects to adviser SLNB recommendations and discussions in band with civic melanoma analytic convenance guidelines and estimates apropos the abridgement in SLNB surgical procedures. The words “anticipates,” “believes,” “estimates,” “expects,” “intends,” “may,” “plans,” “projects,” “will,” “would” and agnate expressions are advised to analyze advanced statements, although not all advanced statements accommodate these anecdotic words. We may not absolutely accomplish the plans, intentions, or expectations appear in our advanced statements and you should not abode disproportionate assurance on our advanced statements. Absolute after-effects or contest could alter materially from the plans, intentions and expectations appear in the advanced statements that we make. These advanced statements absorb risks and uncertainties that could account our absolute after-effects to alter materially from those in the advanced statements, including, after limitation, the risks set alternating in our final announcement filed with the SEC on July 26, 2019 apropos to our Registration Statements on Form S-1 (File Nos. 333-232369 and 333-232796) and our Quarterly Report on Form 10-Q for the division concluded September 30, 2019, filed with the SEC on November 12, 2019, and in our added filings with the SEC. The advanced statements are applicative alone as of the date on which they are made, and we do not accept any obligation to amend any advanced statements, except as may be appropriate by law.
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