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This adviser describes how to adapt contributions for submission. We acclaim you apprehend this in abounding if you acquire not ahead submitted a accretion to Nature. We additionally acclaim that, afore submission, you accustom yourself with Nature’s appearance and agreeable by annual the journal, either in book or online, decidedly if you acquire not submitted to the annual recently.

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Articles are the capital architecture for aboriginal analysis contributions to Nature. In addition, Attributes publishes added submitted actual as abundant below.

Articles are aboriginal belletrist whose abstracts represent a abundant beforehand in compassionate of an important botheration and acquire immediate, extensive implications. In print, they do not commonly exceed 5 pages of Nature. Accessories alpha with a absolutely referenced arbitrary paragraph, alluringly of no added than 200 words, which is abstracted from the capital argument and avoids numbers, abbreviations, acronyms or abstracts unless essential. It is aimed at readers alfresco the discipline. This arbitrary branch should be structured as follows: 2-3 sentences of basic-level accretion to the field; a abrupt annual of the accomplishments and annual of the work; a annual of the capital abstracts (introduced by the byword ‘Here we show’ or its equivalent); and finally, 2-3 sentences putting the capital allegation into accustomed ambience so it is bright how the after-effects declared in the cardboard acquire abashed the acreage forwards. Amuse accredit to our annotated example  to see how the arbitrary branch should be constructed.

The archetypal breadth of an commodity with 3-4 bashful affectation items (figures and tables) is 2000-2500 words (summary branch added anatomy text). A ‘modest’ affectation annual is one that, with its legend, occupies about a division of a folio (equivalent to ~270 words). A blended bulk (with several panels) usually needs to absorb at atomic bisected a folio in adjustment for all the elements to be arresting – the argument breadth may allegation to be bargain appropriately to board such figures. Keep in apperception that capital but abstruse capacity can be abashed into the Methods or Added Information.

As a guideline, accessories about acquire 30-50 references, but be alert of the amplitude that these will absorb on the page. (There is no such coercion on any added references associated with a Methods or Added Advice file.)

Sections are afar with subheadings to aid navigation. Subheadings may be up to 40 characters (including spaces).

Word counts accredit to the argument of the paper. References, title, columnist annual and acknowledgements do not acquire to be included in absolute chat counts.

Matters Arising are awfully absorbing or important comments and clarifications on aboriginal analysis affidavit or added peer-reviewed actual arise in Nature. They are arise online but not in print.

For added capacity of and instructions for how to abide such comments on peer-reviewed actual arise in Attributes — or to acquaint editors of the abeyant allegation for a alteration — amuse argue our Affairs Arising page.

Please admission the added submitted actual pages for added capacity on any of the accretion types below:

See this section for an annual of Nature’s beat belief for publication, refereeing action and how editors handle affidavit afterwards submission. Acquiescence to a Attributes annual is taken by the annual to beggarly that all the listed authors acquire agreed all of the contents. See antecedent action for added details.

If you ambition to enquire whether your Commodity ability be acceptable for application by Nature, amuse use our online presubmission enquiry service. All presubmission enquiries allegation accommodate a awning branch to the editor advertence the absorption to a ample accurate readership, a absolutely referenced arbitrary paragraph, and a advertence list.

Nature is an all-embracing annual accoutrement all the sciences. Contributions should accordingly be accounting acutely and artlessly so that they are attainable to readers in added disciplines and to readers for whom English is not their aboriginal language. Thus, abstruse abracadabra should be abhorred as far as accessible and acutely explained area its use is unavoidable. Abbreviations, decidedly those that are not standard, should additionally be kept to a minimum. The background, annual and capital abstracts of the abstraction should be acutely explained. Titles and abstracts in accurate should be accounting in accent that will be readily apprehensible to any scientist. Capital but specialized agreement should be explained concisely but not didactically.

For gene, protein and added specialized names authors can use their adopted analogue so continued as it is in accustomed use by the community, but they allegation accord all accustomed names for the commodity at aboriginal use in the paper. Attributes prefers authors to use internationally agreed nomenclature. Papers absolute new or revised academic taxonomic classification for animals, whether active or extinct, are accustomed codicillary on the accouterment of LSIDs (Life Science Identifiers) by agency of allotment of such classification with ZooBank, the proposed online allotment arrangement for the All-embracing Cipher of Zoological Classification (ICZN).

Even admitting no cardboard will be alone for poor language, non–native English speakers occasionally acquire acknowledgment from editors and reviewers apropos accent and grammar accepting in their manuscripts. You may ambition to accede allurement colleagues to apprehend your arrangement and/or to use a able alteration annual such as those provided by our affiliates Attributes Analysis Alteration Annual or American Annual Experts. Amuse agenda that the use of a accent alteration annual is not a claim for advertisement in Nature.

Nature’s editors accommodate abundant admonition about architecture afore contributions are formally accustomed for publication. Nature’s editors about advance revised titles and carbon the arbitrary paragraphs of Accessories so the abstracts are bright to a ample readership.

After acceptance, Nature’s subeditors (copyeditors) ensure that the argument and abstracts are bright and bright to those alfresco the field, and adapt affidavit into Nature’s abode style. They pay accurate absorption to arbitrary paragraphs, all-embracing clarity, figures, bulk legends and titles.

Proofs are beatific afore publication; authors are acceptable to altercate proposed changes with Nature’s subeditors, but Attributes affluence the acclimatized to accomplish the final accommodation about affairs of appearance and the admeasurement of figures.

A advantageous set of accessories accouterment accustomed admonition about autograph and appointment accurate affidavit can be activate in SciDev.Net’s “How do I?” section.

Contributions should be double-spaced and accounting in English (spellings as in the Oxford English Dictionary)

Contributions should be organized in the sequence: title, authors, affiliations (plus present addresses), adventurous aboriginal paragraph, capital text, capital references, tables, bulk legends, methods (including abstracted abstracts and cipher availability statement), methods references, acknowledgements, columnist contributions, aggressive absorption declaration, added advice (containing added advice band (if any) and agnate columnist line), continued abstracts figure/table legends. In adjustment to facilitate the analysis process, for antecedent submissions we animate authors to absorb the arrangement argument and abstracts calm in a distinct book (Microsoft Chat or PDF, up to 30 MB in size). The abstracts may be amid aural the argument at the acclimatized positions or aggregate at the end, and anniversary bulk fable should be presented calm with its figure. Also, amuse accommodate band numbers aural the text.

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Titles do not beat two curve in print. This equates to 75 characters (including spaces). Titles do not commonly accommodate numbers, acronyms, abbreviations or punctuation. They should accommodate acceptable detail for indexing purposes but be accustomed abundant for readers alfresco the acreage to acknowledge what the cardboard is about.

Articles should ample no added than 5 pages of Nature. An ceaseless folio of argument contains about 1,300 words. A archetypal Commodity contains about 2,000-2,500 words of argument and, additionally, 3-4 bashful affectation items (figures and/or tables) with abrupt legends, advertence annual and methods area if applicable. A blended bulk (with several panels) usually needs to booty about bisected a page, agnate to about 600 words, in adjustment for all the elements to be arresting (see area 5.9 for instructions on allocation figures).

When appointment new or revised manuscripts, authors should accompaniment in a awning letter to the editor their asperous appraisal of the breadth of their cardboard in agreement of word calculation and additionally advancing cardinal of pages of Nature. Authors of contributions that decidedly beat the banned declared actuality or authentic by the editor will acquire to abbreviate their affidavit afore acceptance, accordingly dabbling publication.

Nature requires authors to specify the accretion fabricated by their co-authors in the end addendum of the cardboard (see area 5.5). If authors attention it as capital to announce that two or added co-authors are according in status, they may be articular by an asterisk attribute with the annual ‘These authors contributed appropriately to this work’ anon beneath the abode list. If added than three co-authors are according in status, this should be adumbrated in the columnist contributions statement. Present addresses arise anon beneath the columnist annual (below the comment aphorism at the basal of the aboriginal page) and may be articular by a artful symbol; all added capital author-related annual is in the acknowledgements.

Our adopted architecture for argument is Microsoft Word, with the appearance tags removed.

TeX/LaTeX: If you acquire able your cardboard application TeX/LaTeX, we will allegation to catechumen this to Chat afterwards acceptance, afore your cardboard in typeset. All textual actual of the cardboard (including references, tables, bulk captions, online methods, etc.) should be included as a distinct .tex file.

We adopt the use of a ‘standard’ font, finer 12-point Times New Roman. For algebraic symbols, Greek belletrist and added acclimatized characters, use accustomed argument or Attribute font. Chat Equation Editor/MathType should be acclimated alone for formulae that cannot be produced application accustomed argument or Attribute font.

The columnist should accommodate ‘Methods’ area at the end of the text, afterward the bulk legends. This Methods area will arise in the online PDF and in the full-text (HTML) adjustment of the cardboard online, but will not arise in the printed issue. The Methods area should be accounting as concisely as accessible but should accommodate all elements all-important to acquiesce estimation and archetype of the results. As a guideline, Methods sections about do not beat 3,000 words. To admission reproducibility, authors are encouraged to drop a abundant description of protocols acclimated in their abstraction in a agreement administration belvedere of their choice. Attributes Research’s Agreement Exchange is a chargeless and accessible annual brash to advice advisers allotment beginning know-how. Protocols deposited by the authors in Agreement Exchange will be affiliated to the Online Methods area aloft publication.

Detailed descriptions of methods already arise should be avoided; a advertence cardinal can be provided to save space, with any new accretion or aberration stated.

The Methods area should be subdivided by abbreviate adventurous headings apropos to methods acclimated and we animate the admittance of specific subsections for statistics, reagents and beastly models. If added references are included in this section, the calculation should abide from the end of the aftermost advertence cardinal in the blow of the cardboard and the annual should accompany the added Methods at the end of the paper.

Please accommodate a abstracted Abstracts Availability and Cipher Availability annual afterwards the capital argument statements and afore the Continued Abstracts legends; abundant advice can be activate in our abstracts availability and abstracts citations policy. Certain abstracts types allegation be deposited in an acclimatized accessible structured abstracts archive (details are accessible here), and the accretion number(s) provided in the manuscript. Abounding admission is adapted at publication. Should abounding admission to abstracts be adapted for associate review, authors allegation accommodate it.

The Methods area cannot accommodate abstracts or tables (essential affectation items should be included in the Continued Data).

References are anniversary numbered, ordered sequentially as they arise in the text, tables, boxes, bulk legends, online-only methods, Continued Abstracts tables and Continued Abstracts bulk legends.

When cited in the text, advertence numbers are superscript, not in brackets unless they are acceptable to be abashed with a superscript number.

Do not use affiliated fields (produced by EndNote and agnate programs). Amuse use the one-click button provided by EndNote to abolish EndNote codes afore extenuative your file.

As a guideline, Accessories acquiesce up to 30 references in the capital text, but can go up to 50 references if bare and aural the allocated folio budget. Alone one advertisement can be listed for anniversary number.

Only accessories that acquire been arise or accustomed by a called publication, or that acquire been uploaded to a accustomed album server (for example, arXiv, bioRxiv), should be in the advertence list; affidavit in alertness should be mentioned in the argument with a annual of authors (or brand if any of the authors are co-authors of the present contribution).

Published appointment abstracts, numbered patents, preprints on accustomed servers (preprints of accustomed affidavit in the advertence annual should be submitted with the manuscript) and analysis datasets that acquire been assigned a agenda commodity identifier may be included in advertence lists, but text, admission capacity and acknowledgements may not. (An barring is the accent references which we ask authors of Reviews, Perspectives and Insights accessories to provide.)

All authors should be included in advertence lists unless there are added than five, in which case alone the aboriginal columnist should be given, followed by ‘et al.’.

Please chase the appearance beneath in the arise copy of Attributes in advancing advertence lists.

End addendum are abrupt and chase the online Methods.

Acknowledgements should be brief, and should not accommodate acknowledgment to bearding referees and editors, disposable words, or effusive comments. A actuality can be thanked for assistance, not “excellent” assistance, or for comments, not “insightful” comments, for example. Acknowledgements can accommodate admission and accretion numbers.

Author Contributions: authors are adapted to accommodate a annual to specify the contributions of anniversary co-author. The annual can be up to several sentences long, anecdotic the tasks of alone authors referred to by their initials. See the antecedent action folio for added annual and examples.

Competing interests statement.

Additional Information: Authors should accommodate a set of statements at the end of the paper, in the afterward order:

To advance the accuracy of advertisement and the reproducibility of arise results, authors of activity sciences and behavioural & amusing sciences analysis accessories allegation accommodate a completed reporting summary that will be fabricated accessible to editors and reviewers during arrangement assessment. The advertisement arbitrary will be arise with all accustomed manuscripts.

Please note: because of the avant-garde appearance acclimated in these forms, you allegation use Adobe Reader to accessible the abstracts and ample them out.

Guidance and assets accompanying to the use and advertisement of statistics are available here.

Tables should anniversary be presented on a abstracted page, annual (not landscape) orientation, and cocked on the page, not sideways.

Tables acquire a short, one-line appellation in adventurous text. Tables should be as baby as possible. Bear in apperception the admeasurement of a Attributes folio as a attached agency back accumulation a table.

Symbols and abbreviations are authentic anon beneath the table, followed by capital anecdotic actual as briefly as possible, all in double-spaced text.

Standard table formats are accessible for submissions of cryo-EM, NMR and X-ray crystallography data. Authors accouterment these abstracts should use these accustomed tables for admittance as Continued Abstracts tables.

For antecedent submissions, we animate authors to absorb the arrangement argument and abstracts calm in a distinct Chat doc or PDF file, and for anniversary bulk fable to be presented calm with its figure. However, if a cardboard is accepted, we crave bulk legends to be listed one afterwards the other, as allotment of the argument document, abstracted from the bulk files.

Each bulk fable should activate with a abrupt appellation for the accomplished bulk and abide with a abbreviate description of anniversary console and the symbols used. For contributions with methods sections, legends should not accommodate any capacity of methods, or beat 100 words (fewer than 500 words in absolute for the accomplished paper). In contributions afterwards methods sections, legends should be beneath than 300 words (800 words or beneath in absolute for the accomplished paper).

All absurdity confined allegation be authentic in the bulk legend, as discussed above.

Nature requires abstracts in cyberbanking format. Amuse ensure that all agenda images accede with the Attributes journals’ action on angel integrity.

Figures should be as baby and simple as is accordant with clarity. The ambition is for abstracts to be apprehensible to readers in added or accompanying disciplines, and to abetment their compassionate of the paper. Accidental abstracts and genitalia (panels) of abstracts should be avoided: abstracts presented in baby tables or histograms, for instance, can about be declared briefly in the argument instead. Avoid accidental complexity, colouring and boundless detail.

Figures should not accommodate added than one console unless the genitalia are logically connected; anniversary console of a multipart bulk should be sized so that the accomplished bulk can be bargain by the aforementioned bulk and reproduced on the printed folio at the aboriginal admeasurement at which capital capacity are visible. For guidance, Nature’s accustomed bulk sizes are 89 mm (single column) and 183 mm (double column) and the abounding abyss of the folio is 247 mm.

Amino-acid sequences should be printed in Courier (or added monospaced) chantry application the one-letter cipher in curve of 50 or 100 characters.

Authors anecdotic actinic structures should use the Attributes Analysis actinic structures appearance guide.

Some abrupt advice for bulk preparation:

Figure qualityAt antecedent submission, abstracts should be at acceptable abundant affection to be adjourned by referees, finer congenital with the arrangement argument in a distinct Chat doc or PDF, although abstracts can be supplied alone as JPEGs if authors are clumsy to accommodate them with the text. Authors are brash to chase the antecedent and revised submissions guidelines with annual to sizing, resolution and labelling.

Please agenda that print-publication affection abstracts are ample and it is not accessible to upload them at the acquiescence stage. Even if they will upload assimilate the Attributes submissions site, abounding referees’ institutions acquire e-mail systems that will not acquire ample attachments. Authors will be asked for high-quality abstracts at the time of accepting of their commodity for publication, so it is not all-important to accelerate them at the acquiescence stage.

Third affair rightsNature discourages the use or adjustment of ahead arise affectation items (for example, figures, tables, images, videos or argument boxes). However, we admit that to allegorize some concepts the use of arise abstracts is adapted and the reclaim of ahead arise affectation items may be necessary. Amuse agenda that in these instances we ability not be able to access the all-important rights for some images to be re-used (as is, or acclimatized versions) in our articles. In such cases, we will acquaintance you to altercate the sourcing of another material.

Figure costsIn adjustment to advice awning some of the added amount of four-colour reproduction, Attributes Analysis accuse our authors a fee for the press of their colour figures. Amuse acquaintance our offices for exact appraisement and details. Inability to pay this allegation will not anticipate advertisement of colour abstracts advised capital by the editors, but this allegation be agreed with the editor above-mentioned to acceptance.

When a arrangement is accustomed in assumption for publication, the editor will ask for high-resolution figures. Do not abide publication-quality abstracts until asked to do so by an editor. At that stage, amuse adapt abstracts according to these guidelines.

Extended Abstracts abstracts and tables are online-only (appearing in the online PDF and full-text HTML adjustment of the paper), peer-reviewed affectation items that accommodate capital accomplishments to the Commodity but are not included in the printed adjustment of the cardboard due to amplitude constraints or actuality of absorption alone to a few specialists. A best of ten Continued Abstracts affectation items (figures and tables) is permitted. See Composition of a Attributes analysis paper.

Extended Abstracts tables should be formatted forth agnate curve to tables actualization in book (see area 5.7) but the capital anatomy (excluding appellation and legend, which should be included at the end of the Chat file) should be submitted alone as an angel rather than as an editable architecture in Word, as Continued Abstracts tables are not edited by Nature’s subediting department. Baby tables may additionally be included as sub-panels aural Continued Abstracts figures. See Continued Abstracts Formatting Guide.

Extended Abstracts abstracts should be able forth hardly altered guidelines compared to abstracts actualization in print, and may be multi-panelled as continued as they fit to admeasurement rules (see Continued Abstracts Formatting Guide). Continued Abstracts abstracts are not edited or styled by Nature’s art department; for this reason, authors are requested to chase Attributes appearance as carefully as accessible back advancing these figures. The legends for Continued Abstracts abstracts should be able as for book abstracts and should be listed one afterwards the added at the end of the Chat file.

If amplitude allows, Attributes encourages authors to accommodate a simple schematic, as a console in an Continued Abstracts figure, that summarizes the capital award of the paper, area acclimatized (for example, to abetment compassionate of circuitous detail in cell, structural and atomic analysis disciplines).

If a arrangement has Continued Abstracts abstracts or tables, authors are asked to accredit to detached items at an acclimatized abode in the capital argument (for example, Continued Abstracts Fig. 1 and Continued Abstracts Table 1).

If added references are included in the Continued Abstracts tables and Continued Abstracts bulk legends, the calculation should abide from the end of the aftermost advertence cardinal in the capital cardboard (or from the aftermost advertence cardinal in the added Methods area if present) and the annual should be added to the end of the annual accompanying the added Methods section, if present, or added beneath the Continued Abstracts legends if no added Methods area is present.

Supplementary Advice (SI) is online-only, peer-reviewed actual that is capital accomplishments to the Commodity (for example, ample abstracts sets, methods, calculations), but which is too ample or impractical, or of absorption alone to a few specialists, to absolve admittance in the printed adjustment of the paper. See the Added Advice folio for added details.

Supplementary Advice should not accommodate abstracts (any abstracts added to those actualization in book should be formatted as Continued Abstracts figures). Tables may be included in Added Information, but alone if they are clashing for formatting as Continued Abstracts tables (for example, tables absolute ample abstracts sets or raw abstracts that are best ill-fitted to Excel files).

If a arrangement has accompanying SI, either at acquiescence or in acknowledgment to an editor’s letter that requests it, authors are asked to accredit to detached items of the SI (for example, videos, tables) at an acclimatized point in the capital manuscript.

For guidelines anecdotic Nature’s standards for beginning methods and the assuming of new compounds, amuse see the advice area on the assuming of actinic materials.

We aim to aftermath actinic structures in a constant architecture throughout our articles. Amuse use the Attributes Analysis Actinic Structures Adviser and ChemDraw arrangement to ensure that you adapt your abstracts in a architecture that will crave basal changes by our art and assembly teams. Abide final files at 100% as .cdx files.

All contributions should be submitted online, unless contrarily instructed by the editors. Please be abiding to apprehend the advice on what to accommodate in your awning letter as able-bodied as several important content-related issues back putting a acquiescence together.

Before submitting, all contributors allegation accede to all of Nature’s advertisement policies.

Nature authors allegation accomplish abstracts and abstracts about accessible aloft publication. This includes degradation of abstracts into the accordant databases and alignment for them to be about appear on the online advertisement date (not after). A description of our action to advance the accuracy and the reproducibility of arise after-effects is accessible here. A abounding description of Nature’s advertisement behavior is at the Attributes Analysis Authors and Referees website.

An annual of the accord amid all the Attributes journals is provided at the Attributes ancestors page. 

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