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NEW YORK & MAINZ, Germany–(BUSINESS WIRE)–Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today appear an acceding with the United Kingdom to accumulation 30 actor doses of their BNT162 mRNA-based vaccine applicant adjoin SARS-CoV-2, currently in development, accountable to analytic success and authoritative approval. Financial accommodation of the acceding were not disclosed, but the acceding were based on the timing of charge and the aggregate of doses.



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“In the face of this all-around bloom crisis, Pfizer’s purpose – breakthroughs that change patients’ lives – has taken on an alike greater urgency. Consequently, we’re harnessing our accurate expertise, and we’re marshaling our accomplishment assets to ensure that the vaccine would be accessible as anon as possible, if our analytic trials prove acknowledged and authoritative approval is granted,” said Albert Bourla, Chairman and Chief Executive Officer, Pfizer. “This acceding is a attestation to our aggregate ambition to accept millions of doses of a vaccine adjoin COVID-19 accessible afore the end of the year. We would like to acknowledge the U.K. government for its charge and abutment in allowance to assure the bodies of the United Kingdom from this baleful virus.”

“I would like to acknowledge the U.K. government for its abutment and putting assurance in us. This acceding is allotment of our charge to abode the communicable by creating a all-around supply. We are in avant-garde discussions with assorted added government bodies and achievement to advertise added accumulation agreements soon. Our ambition charcoal to accompany a safe and able COVID-19 vaccine to abounding bodies about the world, as bound as we can,” said Ugur Sahin, M.D., CEO and Co-founder of BioNTech.



“Finding a vaccine is one way that we will end the communicable and acknowledgment to accustomed life. That is why we are authoritative abiding bodies best at accident in the U.K. are vaccinated adjoin COVID-19 as anon as a safe vaccine becomes available, by partnering with the world’s foremost biologic and vaccine companies,” said Alok Sharma, the U.K.’s Secretary of State for Business, Energy and Industrial Strategy.

The BNT162 affairs is based on BioNTech’s proprietary mRNA technology and accurate by Pfizer’s all-around vaccine development and accomplishment capabilities. The BNT162 vaccine candidates are adeptness analytic studies and are not currently accustomed for administration anywhere in the world. BioNTech is the bazaar allotment holder common and will authority all trademarks for the abeyant product. Both collaborators are committed to developing these atypical vaccines with pre-clinical and analytic abstracts at the beginning of all their decision-making.



The Pfizer/BioNTech vaccine development affairs is evaluating at atomic four beginning vaccines, anniversary of which represents a different aggregate of agent RNA (mRNA) architecture and ambition antigen. On July 1st, Pfizer and BioNTech appear basic abstracts from BNT162b1, the best avant-garde of the four mRNA formulations. The aboriginal abstracts authenticate that BNT162b1 is able to aftermath acrid antibodies in bodies at or aloft the levels empiric in the claret from patients who accept recovered from COVID-19, and this was apparent at almost low dosage levels. Bounded reactions and systemic contest were dose-dependent, about balmy to moderate, and transient. No austere adverse contest were reported.

Recently, two of the companies’ four investigational vaccine candidates (BNT162b1 and BNT162b2) accustomed Fast Track appellation from the U.S. Food and Biologic Administration (FDA). This appellation was accepted based on basic abstracts from Phase 1/2 studies that are currently advancing in the United States and Germany as able-bodied as beastly immunogenicity studies. Added abstracts from the advancing Phase 1/2 analytic trials of the four vaccine candidates will accredit the alternative of a beforehand applicant and dosage akin for an advancing large, all-around Phase 2b/3 assurance and adeptness abstraction that may activate as aboriginal as after this month, awaiting authoritative approval.

If the advancing studies are successful, Pfizer and BioNTech apprehend to be accessible to seek Conditional Marketing Allotment or some anatomy of authoritative approval as aboriginal as October 2020. The companies currently apprehend to accomplish globally up to 100 actor doses by the end of 2020 and potentially added than 1.3 billion doses by the end of 2021, accountable to final dosage alternative from the analytic trial.

In accession to the engagements with governments, Pfizer and BioNTech accept provided an announcement of absorption for accessible accumulation to the COVAX Facility, a apparatus accustomed by Gavi, the Vaccine Alliance, the Coalition for Epidemic Preparedness Innovations (CEPI) and Apple Bloom Organization (WHO) that aims to accommodate governments with aboriginal admission to a ample portfolio of COVID-19 applicant vaccines application a ambit of technology platforms, produced by assorted manufacturers beyond the world.

About Pfizer: Breakthroughs That Change Patients’ Lives

At Pfizer, we administer science and our all-around assets to accompany therapies to bodies that extend and decidedly beforehand their lives. We strive to set the accepted for quality, assurance and amount in the discovery, development and accomplish of bloom affliction products, including avant-garde medicines and vaccines. Every day, Pfizer colleagues assignment beyond developed and arising markets to beforehand wellness, prevention, treatments and cures that claiming the best feared diseases of our time. Consistent with our albatross as one of the world’s arch avant-garde biopharmaceutical companies, we coact with bloom affliction providers, governments and bounded communities to abutment and aggrandize admission to reliable, affordable bloom affliction about the world. For added than 150 years, we accept formed to accomplish a aberration for all who await on us. We commonly column advice that may be important to investors on our website at www.Pfizer.com. In addition, to apprentice more, amuse appointment us on www.Pfizer.com and chase us on Twitter at @Pfizer and @Pfizer News, LinkedIn, YouTube and like us on Facebook at Facebook.com/Pfizer.

Pfizer Disclosure Notice

The advice independent in this absolution is as of July 20, 2020. Pfizer assumes no obligation to amend advanced statements independent in this absolution as the aftereffect of new advice or approaching contest or developments.

This absolution contains advanced advice about Pfizer’s efforts to action COVID-19, the BNT162 mRNA vaccine program, a accord amid BioNTech and Pfizer to advance a abeyant COVID-19 vaccine, an acceding with the United Kingdom to accumulation BNT162 and added abeyant accumulation agreements, including their abeyant benefits, accomplishment and administration and the accepted timing of analytic trials and authoritative submissions, that involves abundant risks and uncertainties that could account absolute after-effects to alter materially from those bidding or adumbrated by such statements. Risks and uncertainties include, amid added things, the uncertainties inherent in analysis and development, including the adeptness to accommodated advancing analytic endpoints, admission and/or achievement dates for analytic trials, authoritative acquiescence dates, authoritative approval dates and/or barrage dates, as able-bodied as the achievability of abortive new preclinical or analytic balloon abstracts and added analyses of absolute preclinical or analytic balloon data; risks associated with basic data; the accident that analytic balloon abstracts are accountable to differing interpretations and assessments, including during the associate review/publication process, in the accurate association generally, and by authoritative authorities; whether and back abstracts from the BNT162 mRNA vaccine affairs will be appear in accurate account publications and, if so, back and with what modifications; whether authoritative authorities will be annoyed with the architecture of and after-effects from these and approaching preclinical and analytic studies; whether and back any biologics authorization applications may be filed in any jurisdictions for any abeyant vaccine candidates beneath the collaboration; whether and back any such applications may be accustomed by authoritative authorities, which will depend on countless factors, including authoritative a assurance as to whether the product’s allowances outweigh its accepted risks and assurance of the product’s adeptness and, if approved, whether any such vaccine candidates will be commercially successful; decisions by authoritative authorities impacting labeling, accomplishment processes, assurance and/or added affairs that could affect the availability or bartering abeyant of any such vaccine candidates, including development of articles or therapies by added companies; accomplishment capabilities or capacity, including whether the estimated numbers of doses can be bogus aural the projected time periods indicated; whether and back a absolute accumulation acceding with the United Kingdom will be reached; whether and back added accumulation agreements will be reached; uncertainties apropos the adeptness to access recommendations from vaccine abstruse committees and added accessible bloom authorities apropos any such vaccine candidates and uncertainties apropos the bartering appulse of any such recommendations; and aggressive developments.

A added description of risks and uncertainties can be begin in Pfizer’s Annual Report on Anatomy 10-K for the budgetary year concluded December 31, 2019 and in its consecutive letters on Anatomy 10-Q, including in the sections thereof captioned “Risk Factors” and “Forward-Looking Advice and Factors That May Affect Approaching Results”, as able-bodied as in its consecutive letters on Anatomy 8-K, all of which are filed with the U.S. Securities and Exchange Commission and accessible at www.sec.gov and www.pfizer.com.

About BioNTech

Biopharmaceutical New Technologies is a abutting bearing immunotherapy aggregation beat atypical therapies for blight and added austere diseases. The Aggregation exploits a advanced arrangement of computational analysis and ameliorative biologic platforms for the accelerated development of atypical biopharmaceuticals. Its ample portfolio of oncology artefact candidates includes abundant and off-the-shelf mRNA-based therapies, avant-garde chimeric antigen receptor T cells, bi-specific checkpoint immuno-modulators, targeted blight antibodies and baby molecules. Based on its abysmal adeptness in mRNA vaccine development and centralized accomplishment capabilities, BioNTech and its collaborators are developing assorted mRNA vaccine candidates for a ambit of communicable diseases alongside its assorted oncology pipeline. BioNTech has accustomed a ample set of relationships with assorted all-around biologic collaborators, including Genmab, Sanofi, Bayer Beastly Health, Genentech, a affiliate of the Roche Group, Genevant, Fosun Pharma, and Pfizer. For added information, amuse appointment www.BioNTech.de.

BioNTech Advanced statements

This columnist absolution contains “forward-looking statements” of BioNTech aural the acceptation of the Private Securities Litigation Reform Act of 1995. These advanced statements may include, but may not be bound to, statements concerning: BioNTech’s efforts to action COVID-19; the timing to admit analytic trials of BNT162 and advancing advertisement of abstracts from these analytic trials; the timing for any abeyant emergency use authorizations or approvals; the abeyant to access into added accumulation agreements with added jurisdictions or the COVAX Facility; the abeyant assurance and adeptness of BNT162; the accord amid BioNTech and Pfizer to advance a abeyant COVID-19 vaccine; and the adeptness of BioNTech to accumulation the quantities of BNT162 to abutment analytic development and, if approved, bazaar demand, including our assembly estimates for 2020 and 2021. Any advanced statements in this columnist absolution are based on BioNTech accepted expectations and behavior of approaching events, and are accountable to a cardinal of risks and uncertainties that could account absolute after-effects to alter materially and abnormally from those set alternating in or adumbrated by such advanced statements. These risks and uncertainties include, but are not bound to: antagonism to actualize a vaccine for COVID-19; the adeptness to aftermath commensurable analytic after-effects in beyond and added assorted analytic trials; the adeptness to finer calibration our productions capabilities; and added abeyant difficulties. For a altercation of these and added risks and uncertainties, see BioNTech’s Annual Report on Anatomy 20-F filed with the SEC on March 31, 2020, which is accessible on the SEC’s website at www.sec.gov. All advice in this columnist absolution is as of the date of the release, and BioNTech undertakes no assignment to amend this advice unless appropriate by law.

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